aldehyde group–based microarray slide (CapitalBio Corporation)
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Aldehyde Group–Based Microarray Slide, supplied by CapitalBio Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/aldehyde group–based microarray slide/product/CapitalBio Corporation
Average 90 stars, based on 1 article reviews
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1) Product Images from "Laboratory and clinical evaluation of a microarray for the detection of ATP7B mutations in Wilson disease in China"
Article Title: Laboratory and clinical evaluation of a microarray for the detection of ATP7B mutations in Wilson disease in China
Journal: Journal of Clinical Laboratory Analysis
doi: 10.1002/jcla.24735
Figure Legend Snippet: Schematic representation of the 24 ATP7B loci and the arrangement of probes in the WD microarray.
Techniques Used: Microarray
Figure Legend Snippet: List of ATP7B mutations selected for microarray detection.
Techniques Used: Microarray, Mutagenesis
Figure Legend Snippet: Determination of cut‐off value for the 24 loci of ATP7B mutation by the microarray detection.
Techniques Used: Mutagenesis, Microarray
Figure Legend Snippet: Representative result of multiplex asymmetric PCR and microarray detection. (A) Twelve bands of PCR products covering all detection sites are distributed in three tubes. The length of the bands and the target fragments in the three tubes are as follows: Tube 1, 287 bp (p.Y741C, p.D765G, p.R778L/Q), 250 bp (p.N1270S, p.T1286I), 172 bp (p.L692P), 137 bp (p.I1148T, p.E1173K); tube 2, 248 bp (p.R919G, p.T935M, p.G943D, p.G948C), 212 bp (p.G869R, p.A874V, p.T888P), 166 bp (p.S975Y, p.G1000R), 130 bp (p.V1106I); and tube 3, 260 bp (p.D196E, p.G250R), 226 bp (p.C490X), 196 bp (c.1708‐5 T>G, p.I592F), and 84 bp (p.I1230T). (B) A representative genotyping result of a clinical sample by microarray detection.
Techniques Used: Multiplex Assay, Microarray
Figure Legend Snippet: Results of microarray detection of ATP7B mutation in 106 suspected WD cases and comparison with that by sequencing.
Techniques Used: Microarray, Mutagenesis, Sequencing
Figure Legend Snippet: Schematic representation of the prevalence of individual ATP7B mutations in Chinese WD patients as detected by the microarray method. p.R778L (50.94%), p.A874V (17.92%), p.P992L (11.32%), p.V1106I (11.32%), and p.I1148T (6.60%) were the most common mutations. ATP7B p.P992L was identified by sequencing.
Techniques Used: Microarray, Sequencing